Advanced threat detection offers protection against advanced malware, zero-day exploits and targeted attacks, which are not detected by the virus scanner or intrusion prevention system.
ATD analyzes files in the Barracuda ATD cloud and assigns a risk score. Local ATD policies then determine how files with high, medium or low risk scores are handled
Basically the file is executed in a sand box in Barracuda Cloud and then analyzed for its behaviour in the environment before delivering to the end user
This real time execution helps you protect from real world threats which most Anti-Viruses and Heuristic Scanners can't detect.
This kind of protection essentially protects you from threats like ransomware which can essentially wreck havoc your IT environment.